Introduction to Drug Synthesis (KIO403)

Definition, scope and the important purpose of synthesis in drug development; drug synthesis history; retrosynthetic analysis; latent polarity and interconvertion of functional group; strategies in synthesis plan; chemoselectivity; regioselectivity; stereoselectivity; examples of commercial drug synthesis.


T. W. Green dan P.G.M. Wuts, Protective Groups in Organic Synthesis, Wiley Interscience, 2006.

Christine L. Willis dan Martin Wills (terj. M. Rudyanto), Sintesis Organik, Surabaya: Airlangga University Press, 2004.        

John Saunders, Top Drugs Top Synthetic Approach, Oxford: Oxford Science Publications, 2000.